Witryna5 maj 2016 · The cells were incubated for 2 h with 5 μM fluorescein isothiocyanate (FITC), rhodamine B (Rho), or naphthofluorescein (NF)-labelled peptide in cellular media. At the end of incubation, the cells were washed with DPBS twice, detached from the plate with 0.25% trypsin, diluted into clear DMEM, pelleted at 250G for 5 min, … WitrynaNaphthofluorescein is a cell-permeable inhibitor of furin (IC50 = 12 μM).{16121} It inhibits furin-mediated cleavage of the pro-form of membrane type-1 matrix metalloproteinase (MT1-MMP), resulting in decreased levels of active MT1-MMP.{16121} This, in turn, suppresses MMP-2 activation and reduces cell motility in CHO cells …
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WitrynaNaphthofluorescein inhibits the interaction between HIF-1 and Mint3. Naphthofluorescein suppresses Mint3-dependent HIF-1 activity and glycolysis in … WitrynaNaphthofluorescein inhibits the invasion of Matrigel by the human fibrosarcoma cell line, HT1080.1 The effects of this furin inhibitor on other furin-mediated processes, in vivo or in vitro, are still unknown. Naphthofluorescein is an inhibitor of Furin. References. 1 Coppola, J.M., Bhojani, M.S., Ross, B.D., et al. pup ozimek
A dual-response naphthofluorescein-based fluorescent probe for …
WitrynaNaphthofluorescein inhibits the invasion of Matrigel by the human fibrosarcoma cell line, HT1080.1 The effects of this furin inhibitor on other furin-mediated processes, in vivo … WitrynaThis paper reports the synthesis, fluorescence properties, and biological applications of naphthofluorescein disulfonate (NFDS-1), as a red fluorescence imaging probe to … Witryna15 lis 2008 · Related sulfonate- and phosphinate-capped naphthofluorescein have been reported for fluorescence detection of peroxide, 11 and superoxide, 26 respectively. … pup pdn