Photocaged quinone methide
WebDec 19, 2024 · Herein, we report photocaged quinone methide (PQM)-based crosslinkers that target nine nucleophilic residues through Michael addition, including Gln, Arg, and … WebJan 4, 2024 · Visible-light-induced [6+4] cycloaddition reactions of ortho-quinone methides have been developed.The reaction of ortho-quinone methides with pentafulvenes in the …
Photocaged quinone methide
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WebLiu J, Li S, Aslam NA, Zheng F, Yang B, Cheng R, Wang N, Rozovsky S, Wang PG, Wang Q, Wang L. Genetically Encoding Photocaged Quinone Methide to Multitarget Protein Residues Covalently in Vivo. J Am Chem Soc. 2024 06 19; 141(24):9458-9462. WebJun 4, 2024 · Quinone methide precursors 12 ‐ 14 protected with alkyldithiomethyl groups of increasing steric demand have been synthesized and converted into PNA conjugates 3 ‐ 5 .
WebOct 1, 2024 · Here we report photocaged quinone methide (PQM)‐based cross‐linkers that are able to multitarget nine nucleophilic residues through specific Michael addition. In … WebOct 23, 2024 · Herein, we report photocaged quinone methide (PQM)-based crosslinkers that target nine nucleophilic residues through Michael addition, including Gln, Arg, and Asn, which are inaccessible to existing chemical crosslinkers. PQM …
Web王鹏，南方科技大学医学院讲席教授，博士生导师。. 中国生物物理学会糖生物学分会会长。. 1984年获南开大学化学理学学士学位，1990年获美国加州大学伯克利分校化学博士学位。. 获美国科学促进会（AAAS）会士，俄亥俄州杰出学者，佐治亚州研究联盟杰出学者 ... WebLiu J, Li S, Aslam NA, et al. (2024) Genetically Encoding Photocaged Quinone Methide to Multitarget Protein Residues Covalently in Vivo. Journal of the American Chemical Society: Yang B, Wang N, Schnier PD, et al. (2024) Genetically Introducing Biochemically Reactive Amino Acids Dehydroalanine and Dehydrobutyrine in Proteins.
WebAug 11, 2024 · An antibody-conjugated photocatalysis system was established and extensively validated, enabling photocatalytic decaging of biotin precursors and proximal quinone methide probes on target cells. Visible-light-controlled selective cell tagging in cell mixture as well as in primary cells from tumor xenografts were demonstrated.
WebJun 19, 2024 · Upon photoactivation, FnbY generated a reactive quinone methide (QM), which selectively reacted with nine natural amino acid residues placed in proximity in … iphone 5s sim freeWebOct 23, 2024 · A lightbulb moment: Photocaged quinone methide (PQM) crosslinkers that target nine nucleophilic amino acids, including Gln, Arg, and Asn, have been developed. … iphone 5s software update 9.3WebLiu J, Li S, Aslam NA, Zheng F, Yang B, Cheng R, Wang N, Rozovsky S, Wang PG, Wang Q, Wang L. Genetically Encoding Photocaged Quinone Methide to Multitarget Protein … iphone 5s slim caseWebPhotocaged Quinone Methide Crosslinkers for Light-Controlled Chemical Crosslinking of Protein-Protein and Protein-DNA Complexes. Article. Oct 2024; Jun Liu; Lingchao Cai; iphone 5s software update not progressingWebJun 6, 2024 · Upon photoactivation, FnbY generated a reactive quinone methide (QM), which selectively reacted with nine natural amino acid residues placed in proximity in … iphone 5s space grey \\u0026 smart phonesWebSep 25, 2024 · Here we report a new chemical conjugation method which photocages highly reactive but chemically selective moieties, enabling the use of protein-inert amines for … iphone 5s software download 7.1 2WebPhotocaged Quinone Methide Crosslinkers for Light-Controlled Chemical Crosslinking of Protein-Protein and Protein-DNA Complexes. Photocaged Quinone Methide Crosslinkers … iphone 5s smart watch